Endocrine Abstracts

Addison’s disease (AD) occurs when 90% of the cortex of Adrenal Glands is affected. Most common causes of AD are autoimmune destruction, tuberculosis, hemorrhage due to meningococcal meningitis, metastatic cancers and adrenoleukodystrophy. AD is associated with other autoimmune disorders e.g., vitiligo, type-1 diabetes or hypothyroidism. Due to non-responsiveness of adrenals to Adrenocorticotrophic hormone (ACTH), α-melanocyte stimulating hormone levels increases and...